Autoimmune
Disorders
Majid Ali, M.D.
Immunity Is the Ability to
Preserve Health
Immunity is generally seen in the
context of microbial infections. This is a very
limited view of immunity. The man-microbe conflicts
are a legacy of microbe-microbe conflicts during the
primordial period—long before humans appeared on the
scene. Oxygen created and adjudicated
microbe-microbe conflicts then, as it does the
man-microbe conflicts now. I came to recognize that
through my clinical work with persons who control
microbial infections well—with or without
antimicrobial drugs — as well as with those who
cannot with any antimicrobial. A large body
of personal phase-contrast microscopic and
biochemical findings in those patients led me to the
conclusion that the fundamental molecular
derangement in the latter is disruption of the
oxygen homeostasis, including
respiratory-to-fermentative shift in ATP production
described previously.
Oxygen Model of
Autoimmune Disorders
My Oxygen Model of Autoimmune
Disorders is an extension of my Oxygen Model of
Health and Disease. It is a unifying model that
explains all aspects of autoimmune disorders—causes,
clinical course, consequences, and control—on the
basis of disturbed oxygen function. The most
important among these compromised and/or blocked
functions are: (1) oxygen signaling; (2) oxygen’s
ATP energy generation; (3) oxygen’s detergent
functions; (4) oxygen’s cellular detox functions;
(5) oxygen-regulated cell membrane and matrix
functions; (6) oxygen’s cellular repair roles.
The Oxygen Model of XXX provides
a simple model that allows physicians to reduce
complexities of diverse clinical syndromes into a
workable
simplicity.
This model predicts that ongoing
research will reveal that components of acidosis
(excess acidity), oxidosis (increased oxidative
stress), and CUD (clotting-unclotting dysequilibrium)
will be found to play important roles in the
pathology and clinical features of autoimmune
disorders
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