Free Courses
Free Videos                                      Free Articles

Science, Health, and Healing Encyclopedia













Ali Oxygen Library
Ali Recipes

Ali SHH-Pedia







Anxiety Course







  Autoimmune Disorders

  Autonomic System

 Bladder, Urinary






 BREAST Health.diseases

Breathing for Healing


BONES, Joints, and Muscles




Children's Readings








Climate Chaos

Collagen Disorders


Current Topics









Energy Healing











Gall BladderStones




GUT Evolution



      Small Intestine
      Rectum and Anus


Healing Stories







Immune System







Kitchen Matters


Lap Dog Journalists



Lou Gehrig ALS



Lyme Disease, Acute

Lyme Disease, Chronic

Lymphatic System





Mental Health







Multiple Sclerosis








Basic Course Advanced Course
Oxygen and Aging
Oxygen Therapeutics
Oxygen -Environment
Oxygen and 9/11
Oxygen Models of Diseases
Oxygen and Origin of Life



Pancreas Pancreatitis

Parkinson's Disease

Philosophy of Healing

Poems Drone Democracy
Selected Poems

Polycystic Ovarian Synd

Poetry of Dr.Ali






Respiratory System




Sinusitis & Polyps



Sodium Salt



Small Intestine



  Stories of Soul's Sweat









Toxic Womb State

Pre-birth PTSD




Urinary System



Video Seminars on Natural Healing

Viral Infections

Recent Videos

Store DVD/Books


Weight Loss

Yeast Syndromes






Dr. Ali's Oxygen and Aging Course

Oxygen Governs the Aging Process

Majid Ali, M.D.

Oxygen is the organizing influence of human biology and governs the aging process. From this simple idea I develop two other dominant themes of this book. First, dysfunctional oxygen metabolism (dysoxygenosis) is the primary mechanism of cellular aging and will be the single most important threat to the human life span in the coming decades. Second, a growing understanding of relationships among man's internal and external environments will govern all our plans for preserving health and reversing disease.

Those simple ideas form the core of my oxygen theory of aging.1-4 But why shouldn't the aging-genes be on the center stage?, some readers might ask. Why not focus on antioxidants?, some others might ask. Should not those factors form the core of any theory of aging? My view is that neither genes nor antioxidants can work well in the presence of dysfunctional oxygen metabolism. I marshal several lines of evidence to support my view.

This book is not about low-fat diets for living longer. The Japanese eat a very low-fat diet and live longer than people in any other country of the world. The Swiss have a very high-fat diet and longer lifespan than any other people except the Japanese. So much for the low-fat and high-fat enthusiasts.

Neither is this book about taking cholesterol-lowering drugs to extend life. Cholesterol is an antioxidant. Coronary heart disease is caused by oxidative injury. Blaming healthy (unrancid, unoxidized) cholesterol for heart disease is as silly as blaming water for illness. Yes, excess rancid cholesterol threatens health just as drinking polluted water does, but the problem is rancidity of cholesterol as it is pollution in water. Nearly all trials of cholesterol-lowering drugs show a reduction in the rate of heart attacks of less than one percent. That means more than 990 of every 1,000 persons who take such drugs get no benefits at all. It is important to point out that all cholesterol-lowering drugs carry a risk of causing cancer, liver disease, chronic fatigue, and other problems. In 1997, for professional readers, my colleague, Omar Ali, and I discussed this subject at length in The Journal of Integrative Medicine.1

The true story of drug therapies for high blood pressure to prolong life is the same. A large number of recent studies clearly show that most people who were administered drugs for high blood pressure for years did not benefit from those therapies. There is broad consensus now that what was considered "mild" hypertension does not increase the risk of heart attacks, stroke, and kidney disease. Even the staunchest supporters of the use of drugs for mild hypertension now agree that millions of persons have been needlessly given drugs for decades. Indeed, over 95% of persons who are diagnosed with the so-called mild hypertension respond well to water therapy, meditation, optimal choices in the kitchen, and gentle, non-goal-oriented exercise.

Gene Therapy Will Prolong ife Span Only When Oxygen Homeostasis Is Preserved

In Oxygen and Aging (2000), I predicted that gene therapies will not extend human life span. For several years now, the gene researchers have intoxicated with the promise of extending life span and of miraculous cures with gene therapies of diseases by the bundle. I have believed for an equally long number of years that gene therapy will have limited benefits for a very small number of people with rare genetic disorders, but only if the oxygen metabolism of those persons can be preserved by natural supportive therapies. The principal reason for my belief is that the language of genes is far more complex than, say, the English language with its mere 26 letter-alphabet. There are an estimated 100,000 genes in the human genome and, in my view, this is likely to prove to be a gross underestimate. Beyond the simple matter of a 26- letter alphabet versus 100,000 genes is the far more important issue of genes reading and responding to their microenvironment, something that letters in words cannot do. Genes not only change their behavior in response to environment, but also alter the behavior of other genes. Of course, the environment also changes the structure of genes. In this volume I present my view that the oxygen order of human biology profoundly affects the function of genes, and we will succeed with gene therapies only to the degree that we can preserve oxygen metabolism of the recipient of such therapies. The claim of living longer by taking out the faulty genes and replacing them with new ones is pure Alice-in-Wonderland.

The drug industry seeks to extend human life span with drugs in interesting ways. Read about a fascinating story published in the New York Times" at  Un-Aging With a Drug.

The use of drug therapies, though necessary for acute illness, is essentially blockade medicine. All commonly used drugs block essential cellular channels, receptors, enzymes, pumps, and mediators of the healing response. It is frivolous to think that the human lifespan can be prolonged by blocking essential cell functions. It is possible that some drugs may offer limited benefits to some people, but only as long as the fundamental oxygen order of human biology can be preserved. One simple but telling argument for my view is this: In the United States, more money is spent on health care than in any other country in the world and yet the life expectancy rate here is among the lowest in developed countries.


Anti-aging Industry

I am much amused by the enthusiasm of the gurus of the anti-aging industry. Some of them have declared aging to be a disease, treatable with their favored products they sell. When I listen to them or read what they write, I wonder if they understand their stuff. I do not. I have never seen a spoiled peach become unspoiled, a rotten egg turn unrotten, or decomposed grass become undecomposed. Nor have I seen any anti-aging guru to "un-age" himself. I eagerly await the time that some 60-year-old expert will become 45 years old. I continue to search for any reasonable basis for their excitement. So far, what I have seen is nothing but misleading claims similar to those of merchants of cholesterol-lowering drugs.

Anti-aging Hormones

Many anti-aging gurus are full of ideas for prescriptions of anti-aging hormones. It is evidently true that natural hormones are essential for healthful aging. But there is a big difference between studying changes in the hormone levels as we advance in age and claims of the ability of hormones to anti-age people. Anti-aging gurus do not conduct any of their own studies. They fondly cite studies conducted by others with mice or medical students for weeks or months. Their game is to sell their products by promises of extended lifespan for decades, no matter how irrelevant the studies they cite are to their merchandise.

A Scientist Has No Paradigm

A Scientist has but one allegiance —to the truth in his observations. We begin to grow when we learn to observe. A theory may be proposed only to explain observations. One must observe first. I write this book to present my clinical and experimental observations about the oxygen order of human biology and how violation of that order leads to dysfunctional oxygen metabolism. For the advanced and professional readers, I published my observations in a series of articles.2-14 My guidelines for healthful aging are based on those observations made during the last four decades. The oxygen theory of aging I propose in this book is my attempt to shed some light on the mechanisms that underlie my observations.

The Dysox Model of Aging

In Spontaneity of Oxidation and Aging (1983), I proposed The Oxidative Model of Aging. In Oxygen and Aging (2000), I marshaled a large body of evidence to support my model.  See  The dysox model of aging  for a summary.

For additional reading on the subject, I suggest my book Oxygen and Aging (2000), available at




Related Articles

k Aging

k  Dr. Ali's Course on Aging

k    Respiratory-to-Fermentative (RTF) Shift in ATP Generation

k  The Oxygen Model of Aging

k  Premature Aging and Early Dying

k  Oxygen Model of Premature Aging

k The dysox Model of Aging

k  Falling Life Expectancy

k   Caloric Restriction Theory of Aging

k   Protein Cross-linking Theory of Aging

k   Fee radical Theory of Aging

k  Origin of Life, Origin of Disease

k Dr. Ali's Course on Oxygen

k  Oxygen Literacy

k  Oxygen Intelligence

k  Oxygen Is the Primal Nutrient

k  History of Oxygen

k  Oxygen's Three-Legged Throne

k The Oxygen Model of Diseases

k Oxygen Kaleidoscope

k Dysox: Energy and Detox Failure in Cells


k  Oxygen-Driven Energetics: An Intelligent Design

k  Respiratory-to-Fermentative (RTF) Shift in ATP Production 

k  Fermentation: Good, Bad, and Ugly

k The Oxygen Model of Disease

k Oxygen-In-Acids-Out Healing Series

k  Oxygen's Three-Legged Throne

k  Beginning of Life

k Dysox: Energy and Detox Failure in Cells

k Molecular Biology of Oxygen Advanced

k  The dysox Model of Aging

k The Oxygen Model of Disease

k Oxygen Kaleidoscope

k  Oxygen's Three-Legged Throne

k Dysox: Energy and Detox Failure in Cells

k Molecular Biology of Oxygen Advanced

k What Does Chlorophyll Reveal About the Origin of Life on the Planet Earth?

k  Origin of Life, Origin of Disease

k  Oxygen-Driven Energetics: An Intelligent Design

k  Respiratory-to-Fermentative (RTF) Shift in ATP Production 

k Re-Thinking the Immune System

k What Does Chlorophyll Reveal About the Origin of Life on the Planet Earth?

k Dysox: Energy and Detox Failure in Cells

k Free YouTube Course on Energy Events in Health and Healing

k Oxidation and Oxidosis

k Oxygen Model of Heart Disease

k Oxygen Model of Kidney Disease

k Oxygen Model of Asthma

k Oxygen Model of Chronic Fatigue Syndrome

k Oxygen Model of Heart Fibromyalgia

k Free YouTube Course on Energy Events in Health and Healing

k Why Not Hydrogen for Healing?

k AA Oxidopathy -The Core Mechanism of Ischemic Heart Disease

k Improved Myocardial Perfusion EDTA Infusions

k  Oxystatic Therapies

k Respiratory-to-Fermentative (RTF) Shift

k What Is Inflammation?

k  Ali M. Cancer, Oxygen, nd Pantotropha .

k The dysox Model of Aging

k The Dysox Model of Diabetes and De-Diabetization

k  Oxygen, Insulin Toxicity, and Inflammation,

k Castor Oil Rubs for Colicky Babies and Children

k Infla-Oil Protocols for Arthritis

k  List of Oxygen Models of Diseases




* Ali M. Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Energy Deficit States. Townsend Letter for Doctors and Patients. 2004. August/Sept. issue. 64-65.

 * Ali M. Hydrogen peroxide therapies: Recent Insights into oxystatic and antimicrobial actions. Townsend Letter for Doctors and Patients. 2004, 255;140-143.

* What Does Chlorophyll Reveal About the Origin of Life on the Planet Earth?

* Ali M. Cancer, Oxygen, and pantotropha — Part I. Townsend Letter for Doctors and Patients. 2004;256:98-102.

Tutorial GG.11 Ali M. The dysox model of aging. Townsend Letter for Doctors and Patients.2005;269:130-134.


* Un-Aging With a Drug?

Tutorial GG.11 Ali M. The dysox model of aging. Townsend Letter for Doctors and Patients.2005;269:130-134.

* Tutorial GG.16 The Dysox Model of Diabetes and De-Diabetization Potential. Townsend Letter-The examiner of Alternative Medicine. 2007; 286:137-145.

* Tutorial GG.31 Ali M. Oxygen, Insulin Toxicity, Inflammation, And the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. October, 2009.

* Tutorial GG.32 Ali M. Insulin Reduction and EDTA Chelation: Two Potent and Complementary Approaches For Preventing and Reversing Coronary Disease. Oxygen, Insulin Toxicity, Inflammation, and the Clinical Benefits of Chelation - Part II. Townsend Letter-The examiner of Alternative Medicine. 2010;323:74-79. June 2010.



1. Ali M. Spontaneity of Oxidation in Nature And Aging. Monograph. 1983. Teaneck, New Jersey.

2. Ali M. Spontaneity of Oxidation in Nature Is the true cause of Aging in Humans and Root Cause of All Disease. page 199-304, RDA: Rats, Drugs and Assumption. 1995. Life Span Press, Denville, New Jersey.

3. Ali M. Lifespan Molecules. The Cortical Monkey and Healing. page 18, 1990. Institute of Preventive Medicine, Bloomfield, New Jersey.

4. Ali M, Ali O. AA oxidopathy: the core pathogenetic mechanism of ischemic heart disease. J Integrative Medicine 1997;1:1-112.

5. Ali M. Oxidative coagulopathy in fibromyalgia and chronic fatigue syndrome. Am J Clin Pathol 1999; 112:566-7.

6. Ali M. The basic equation of life. The Butterfly and Life Span Nutrition. 1992. The Institute of Preventive Medicine Press, Denville, New Jersey, pp 225-236.

7. Ali M. Oxidative theory of cell membrane and plasma damage. RDA: Rats, Drugs and Assumptions. pp 281-302, 1995. Life Span, Denville, New Jersey.

8. Ali M. Adrenergic hypervigilence. What Do Lions Know About Stress? pp 137-172, 1996. Life Span Press, Denville, New Jersey, .

9. Ali M. Oxidative regression to primordial cellular ecology (ORPEC): evidence for the hypothesis and its clinical significance. J Integrative Medicine 1988;2:4-55.

10. Ali M. Amenorrhea, oligomenorrhea, and polymenorrhea in CFS and fibromyalgia are caused by oxidative menstrual dysfunction. J Integrative Medicine 1998;3:101-124.

11. Ali, M. Oxidative menopausal dysfunction (OMD-II): hormone replacement therapy (HRT) or receptor restoration therapy (RRT)? J Integrative Medicine 1998;3:125-139.

12. Ali M. Ali O. Fibromyalgia: an oxidative-dysoxygenative disorder (ODD) J Integrative Medicine 1999;1:17-37.

13 Ali M. Darwin, oxidosis, dysoxygenosis, and integration. J Integrative Medicine 1999;1:11-16.

14. Ali M. The oxidative-dysoxygenative perspective of allergic disorders. J Integrative Medicine 2000;4:15-24.



Who Is Dr. Ali?

Dr. Ali's Full CV

Peer Reviews of Dr. Ali' Work


Dr. Ali's Philosophy



VIDEO Courses

Philosophy of Integrative medicine 

Dr. Ali's Recent Videos

Click here to order Prof. Ali's Video Courses, digital aand print books, DVD seminars, and lectures on CD sets.


Now Available as
Instant Download

Integrative Protocols -
Vol 12 Principles and Practices
of Integrative Medicine

Dr. Ali's
IV and IM formulations

E-Book 12

Integrative Protocols -
Vol 11 Principles and Practices
of Integrative Medicine
E-Book 11

Dr. Ali discusses Dysoxygenosis and varying chronic diseases.


Book Diabetes

Instant Download